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Phytopure® NMN + Fisetin ADVANCED

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R1548,49

• Phytopure® NMN + Fisetin Advanced is an innovative healthy ageing supplement which provides 500mg NMN and 50mg Fisetin per capsule.

• Contains patented Uthever® NMN which is proven to increase NAD+ levels in humans and has a 99% concentration of beta NMN for optimal effectiveness.

• With added Fisetin which removes zombie cells that cause inflammation and ageing.

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Free delivery on orders over R600

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Indications: 

NMN is a naturally occurring form of Vitamin B3 that is studied for slowing ageing and for preventing diseases of ageing. Dietary NMN is converted to nicotinamide adenine dinucleotide (NAD+), a coenzyme in all living cells which is required for numerous biological processes. NAD+ levels naturally decline with age, reaching less than 50% of youthful levels by middle age.

Decreased NAD+ levels have been attributed to increased inflammation and oxidative stress as well as to the development of age-related conditions such as hypertension, cognitive decline, and type 2 diabetes.

Phytopure® NMN (with Fisetin) Advanced is an innovative nutraceutical formulated to support healthy NAD+ levels, remove senescent cells, support optimal function of the immune system and promote healthy ageing.

Studies have found that NMN supplements assist with increasing blood NAD+ levels in different populations, resulting in the following benefits:

  1. Mitochondrial health: Mitochondria, often referred to as the “powerhouses” of cells, playing a vital role in energy production. NMN supports mitochondrial function which has broad implications for overall health and vitality.
  2. DNA repair: NAD+ plays a role in the repair of DNA. By boosting NAD+ levels, NMN might support the body’s ability to repair DNA damage, which is associated with ageing.
  3. Protection against age-related diseases: Studies suggest that NMN supplementation might assist with various age-related conditions like cardiovascular diseases, neurodegenerative diseases, and metabolic disorders such as type 2 diabetes.
  4. Improvement in energy metabolism: NMN has been shown to improve energy metabolism, potentially leading to enhanced physical performance and stamina.
  5. Support for brain health: NMN may offer neuroprotective benefits. Some studies suggest that NMN can support cognitive function and might be beneficial in the context of neurodegenerative diseases.
  1. Anti-inflammatory effects: Studies suggest that NMN can modulate inflammation, which is a fundamental mechanism underlying many chronic diseases.


As you age, you also accumulate more and more senescent cells (or zombie cells) which are cells that refuse to die, creating toxins that cause inflammation and play a causal role in ageing.

Fisetin is a naturally occurring flavonoid found in various fruits and vegetables as well as a powerful natural senolytic. Fisetin has been shown to eliminate a significant number of senescent cells, which in turn reduces the inflammation and ageing these cells cause.

Other benefits of fisetin include:

  • Promotion of NAD+ Production
  • Protection against age-related diseases
  • Improvement of energy metabolism
  • Support for brain health
  • DNA repair
  • Anti-inflammatory effects
  • Antioxidant properties
  • Supports cardiovascular health
  • Improves blood sugar regulation
  • Promotes skin health


Phytopure® NMN (with Fisetin) Advanced is an innovative healthy ageing supplement which provides 500mg NMN and 50mg Fisetin per capsule.

More about this product:

Why choose this product?

1. Patented NMN
  • Contains patented UTHEVER® NMN which is the only NMN proven in a published clinical trial to effectively increase NAD+ levels in humans.
2. Clean Label
  • UTHEVER® uses NR as the raw material which is the FDA GRAS (generally recognized as safe), with multiple detection methods to ensure product quality and safety from the sources.
  • In the process of enzymatic biosynthesis of UTHEVER®, the biological enzyme used is self-developed, designed to have a high conversion rate and high selectivity. This ensure the quality and safety of the product and reduction of pollutants.
3. Concentration of NMN
  • According to research, the best NMN supplements contain 98% pure NMN or higher. The concentration is key in providing the most active benefits. Some supplements have proper doses but incorrect concentrations.
  • Phytopure® NMN contains β type, 99% UTHEVER®NMN at 500mg per capsule which is an effective therapeutic dose.
4. Added Fisetin
  • Phytopure® NMN (with Fisetin) Advanced contains 50mg of Fisetin per capsule providing complementary benefits to NMN for the indication of healthy ageing.


We recommend this product is taken alongside our Reversatrol™ and Phytopure® Quercetin with Pomegranate for further synergistic benefits.

About Phytoceutics®:

Phytoceutics® represents a culmination of years of dedication and commitment to natural healthcare. As a family-founded company, Phytoceutics® has evolved into an international healthcare group providing a diverse and expanding portfolio of innovative, high-quality, and ethically sourced nutraceutical products and brands.

The Phytoceutics® product portfolio has grown significantly over the years and continues to develop as we invest significantly in R&D, uncovering new vitamins, minerals, amino acids, botanicals, phytochemicals, beneficial bacteria (and more) that can help optimize your health. Staying true to our promise of being fastidious when representing brands and sourcing raw ingredients, we ensure that only products of the highest, purest quality, which are highly bioavailable and absorbable are offered. On top of this, it is of utmost importance to Phytoceutics® that we are environmentally ethical, reducing our global footprint as much as possible.
Indications: 

NMN is a naturally occurring form of Vitamin B3 that is studied for slowing ageing and for preventing diseases of ageing. Dietary NMN is converted to nicotinamide adenine dinucleotide (NAD+), a coenzyme in all living cells which is required for numerous biological processes. NAD+ levels naturally decline with age, reaching less than 50% of youthful levels by middle age.

Decreased NAD+ levels have been attributed to increased inflammation and oxidative stress as well as to the development of age-related conditions such as hypertension, cognitive decline, and type 2 diabetes.

Phytopure® NMN (with Fisetin) Advanced is an innovative nutraceutical formulated to support healthy NAD+ levels, remove senescent cells, support optimal function of the immune system and promote healthy ageing.

Studies have found that NMN supplements assist with increasing blood NAD+ levels in different populations, resulting in the following benefits:

  1. Mitochondrial health: Mitochondria, often referred to as the “powerhouses” of cells, playing a vital role in energy production. NMN supports mitochondrial function which has broad implications for overall health and vitality.
  2. DNA repair: NAD+ plays a role in the repair of DNA. By boosting NAD+ levels, NMN might support the body’s ability to repair DNA damage, which is associated with ageing.
  3. Protection against age-related diseases: Studies suggest that NMN supplementation might assist with various age-related conditions like cardiovascular diseases, neurodegenerative diseases, and metabolic disorders such as type 2 diabetes.
  4. Improvement in energy metabolism: NMN has been shown to improve energy metabolism, potentially leading to enhanced physical performance and stamina.
  5. Support for brain health: NMN may offer neuroprotective benefits. Some studies suggest that NMN can support cognitive function and might be beneficial in the context of neurodegenerative diseases.
  1. Anti-inflammatory effects: Studies suggest that NMN can modulate inflammation, which is a fundamental mechanism underlying many chronic diseases.


As you age, you also accumulate more and more senescent cells (or zombie cells) which are cells that refuse to die, creating toxins that cause inflammation and play a causal role in ageing.

Fisetin is a naturally occurring flavonoid found in various fruits and vegetables as well as a powerful natural senolytic. Fisetin has been shown to eliminate a significant number of senescent cells, which in turn reduces the inflammation and ageing these cells cause.

Other benefits of fisetin include:

  • Promotion of NAD+ Production
  • Protection against age-related diseases
  • Improvement of energy metabolism
  • Support for brain health
  • DNA repair
  • Anti-inflammatory effects
  • Antioxidant properties
  • Supports cardiovascular health
  • Improves blood sugar regulation
  • Promotes skin health


Phytopure® NMN (with Fisetin) Advanced is an innovative healthy ageing supplement which provides 500mg NMN and 50mg Fisetin per capsule.

More about this product:

Why choose this product?

1. Patented NMN
  • Contains patented UTHEVER® NMN which is the only NMN proven in a published clinical trial to effectively increase NAD+ levels in humans.
2. Clean Label
  • UTHEVER® uses NR as the raw material which is the FDA GRAS (generally recognized as safe), with multiple detection methods to ensure product quality and safety from the sources.
  • In the process of enzymatic biosynthesis of UTHEVER®, the biological enzyme used is self-developed, designed to have a high conversion rate and high selectivity. This ensure the quality and safety of the product and reduction of pollutants.
3. Concentration of NMN
  • According to research, the best NMN supplements contain 98% pure NMN or higher. The concentration is key in providing the most active benefits. Some supplements have proper doses but incorrect concentrations.
  • Phytopure® NMN contains β type, 99% UTHEVER®NMN at 500mg per capsule which is an effective therapeutic dose.
4. Added Fisetin
  • Phytopure® NMN (with Fisetin) Advanced contains 50mg of Fisetin per capsule providing complementary benefits to NMN for the indication of healthy ageing.


We recommend this product is taken alongside our Reversatrol™ and Phytopure® Quercetin with Pomegranate for further synergistic benefits.

About Phytoceutics®:

Phytoceutics® represents a culmination of years of dedication and commitment to natural healthcare. As a family-founded company, Phytoceutics® has evolved into an international healthcare group providing a diverse and expanding portfolio of innovative, high-quality, and ethically sourced nutraceutical products and brands.

The Phytoceutics® product portfolio has grown significantly over the years and continues to develop as we invest significantly in R&D, uncovering new vitamins, minerals, amino acids, botanicals, phytochemicals, beneficial bacteria (and more) that can help optimize your health. Staying true to our promise of being fastidious when representing brands and sourcing raw ingredients, we ensure that only products of the highest, purest quality, which are highly bioavailable and absorbable are offered. On top of this, it is of utmost importance to Phytoceutics® that we are environmentally ethical, reducing our global footprint as much as possible.
Ingredient Amount
UTHEVER® Niacinamide mononucleotide (NMN) 500mg
Fisetin 50mg
Product Information
Recommended Use Adults 18 years and older: Take 1-2 capsules daily with or after food, or as recommended by your healthcare provider.
Supplement Facts
Capsules per container 60
GMO Free Yes
Gluten Free Yes
Sugar Free Yes
Suitable for Vegans and Vegetarians Yes
Recyclable Packaging Yes
Warnings and Special Precautions
Not Suitable for Children Yes
Consult Healthcare Provider Consult a relevant healthcare provider if you are pregnant or breastfeeding.
Category D34.12: Complementary medicine
SAHPRA Evaluation This unregistered medicine has not been evaluated by the SAHPRA for its quality, safety, or intended use.

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Frequently Asked Questions

Can I take NMN and fisetin together?

Yes, you can take NMN and fisetin simultaeneously. Combining these naturally derived compounds may have synergistic/complementary effects resulting in healthy ageing and potent antioxidant properties.

NMN is a NAD+ precursor, vital for cellular processes like energy metabolism in the mitochondria. Fisetin, a flavonoid, has anti-inflammatory and antioxidant properties protecting cells against oxidative stress.

Effects of NMN can vary based on many factors like dosage, formulation, different metabolism function for each individual etc. Some may notice benefits within days, while others might take weeks or months to observe a beneficial effect.

Supplements are not used to treat, modify, or prevent any disease or illness. Supplements may complement health, supplement diet, or have a nutritional effect.

This product contains patented UTHEVER® NMN: according to their dosing suggestion – take with or after food.

There is no requirement that you have to take resveratrol with NMN. However, some studies suggest that resveratrol and NMN may have synergistic effects. Both compounds have antioxidant properties that may assist with healthy ageing, DNA repair and promotion of overall health.

Some evidence suggest that NMN may support collagen production indirectly:

Collagen is a protein that plays a crucial role in skin health, and its production is influenced by various factors, including NAD+ levels. NMN is a precursor to NAD+, a coenzyme involved in cellular energy production and DNA repair.

Boosting NAD+ levels with NMN may support cellular processes that contribute to collagen synthesis. However, direct evidence linking NMN supplementation to collagen improvement is limited, and more research is needed to fully understand its effects on collagen production and skin health.

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Phytopure® NMN + Fisetin ADVANCED
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